By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
MindBody Wellness Toolbox
  • 🔥 Trending:
  • Fitness and Exercise
  • Chronic Conditions
  • Nutrition and Diet
  • Home
  • Nutrition and Diet
  • Fitness and Exercise
  • Mental Health
  • Weight Management
  • Chronic Conditions
  • Store
Reading: Study investigates prescribing patterns of cognitive impairment-associated drug
MindBody Wellness ToolboxMindBody Wellness Toolbox
0
Font ResizerAa
  • Home
  • Nutrition and Diet
  • Fitness and Exercise
  • Mental Health
  • Weight Management
  • Chronic Conditions
  • Store
Search
  • Home
  • Nutrition and Diet
  • Fitness and Exercise
  • Mental Health
  • Weight Management
  • Chronic Conditions
  • Store

Must Read

🧬 How Your DNA Affects Aging — And 3 Powerful Tools to Support It

Small Chocolate Chip Cookies | Diethood

Leverage Your Zodiac for Intuitive Connections

Pro ice hockey: Mental health & burnout linked to increased concussions

Experts Advise Against DIY Pore Strips: Safer Alternatives

Follow US
  • Contact Us
  • Blog Index
  • Complaint
  • Advertise
Copyright © 2024 MindBody Wellness Toolbox. All Rights Reserved.
MindBody Wellness Toolbox > Blog > Chronic Conditions > Study investigates prescribing patterns of cognitive impairment-associated drug
Chronic Conditions

Study investigates prescribing patterns of cognitive impairment-associated drug

Cjaywellness By Cjaywellness July 10, 2024
Share
3 Min Read
SHARE
flipboard
Flipboard
Google News

The Impact of Tricyclic Antidepressants on Cognitive Function in Adults with Diabetes and Peripheral Neuropathy

Many adults with diabetes who also suffer from the complication of peripheral neuropathy often find themselves prescribed medications at doses and for durations that could potentially increase their risk of cognitive impairment. This worrying trend has prompted a new study led by Research Scientist Noll Campbell, PharmD, M.S., from the Regenstrief Institute and Purdue University College of Pharmacy, which sheds light on prescribing patterns of tricyclic antidepressants for the treatment of diabetic peripheral neuropathy.

With a study population that included adults over 18 years of age and was comprised of 44 percent White and 42 percent Black individuals, the researchers discovered that nearly two-thirds of the prescribed tricyclic antidepressants exceeded the dosage threshold associated with an increased risk of dementia in older adults. Alarmingly, Black patients were more likely to be prescribed these drugs at higher doses, significantly elevating their risk for dementia compared to their White counterparts.

Research conducted by the Regenstrief Institute has consistently shown a link between the long-term use of anticholinergic medications, such as tricyclic antidepressants, and cognitive impairment, including dementia. Studies suggest that the use of anticholinergics in older adult populations can increase the risk of dementia by 30 to 50 percent.

Diabetic peripheral neuropathy is a common syndrome among adults with long-term or uncontrolled Type I or Type II diabetes, resulting in damage to neurons that impairs neurological function in the extremities. This condition can cause pain, numbness, vulnerability to infection, and other complications. Despite current diabetes care guidelines recommending the use of tricyclic antidepressants to manage pain and concurrent depression, there is a lack of awareness regarding the risks associated with long-term usage of these drugs, which target the nerves and brain.

“Our analysis of electronic health records revealed that tricyclic antidepressants were being prescribed to individuals with diabetes for durations of up to five, eight, or even nine years, exposing about two-thirds of users to a higher risk of dementia,” explained Dr. Campbell, an expert in aging brain and pharmacy services research. “Deprescribing these medications could potentially reduce the risk of dementia, and there are alternative drugs available that do not pose a threat to cognitive function while being equally effective. Unfortunately, we found minimal evaluation of drug efficacy in routine clinical care settings.”

“Older Black adults in the U.S. are disproportionately affected by dementia compared to their White counterparts. Is this disparity due to the disease itself, or could it be attributed to the medications they are prescribed? While modifying the disease may be challenging, we have the power to alter the types of medications utilized to manage these conditions,” Dr. Campbell noted.

Cjaywellness July 10, 2024 July 10, 2024
Share This Article
Facebook Twitter Print
By Cjaywellness
🧠 CJay Wellness | RN, PMHNP – Founder of MindBodyWellness Toolbox CJay is a compassionate healthcare professional and the voice behind MindBodyWellness Toolbox. As a Registered Nurse (RN) and Psychiatric-Mental Health Nurse Practitioner (PMHNP) with over 20 years of experience, CJay is on a mission to bridge the gap between mental health, physical wellness, and holistic self-care. Through insightful, evidence-based blog posts, CJay shares practical tools and supportive guidance to help readers manage stress, improve sleep, boost mood, and feel more balanced—both mentally and physically. Each post is infused with clinical knowledge and real-world compassion for those navigating life’s challenges. Whether you're exploring wellness for the first time or looking to deepen your journey, CJay Wellness is here to provide resources that empower you from the inside out.
Previous Article Effects of trauma exposure on mental health and social engagement in refugees
Next Article Nightly Habit Adds Nearly 5 Years to Life
Leave a comment Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Must Read

🧬 How Your DNA Affects Aging — And 3 Powerful Tools to Support It

Spice up Taco Tuesday with Roasted Veggie Tacos

Free printable running log & tracker for 2024 miles

Nutritious Peanut Butter Snacks – The Fitnessista

Quest Chocolate Peanut Butter Rice Cakes

The Impact of Genes on Obesity Trends

- Advertisement -
Ad image

You Might also Like

Pro ice hockey: Mental health & burnout linked to increased concussions

The Link Between Concussion, Mental Health, and Alcohol Consumption in Elite Hockey Players Elite ice…

By 5 Min Read

Precision medicine identifies high-risk obesity subgroups

Obesity is a chronic and complex disease characterized by abnormal and/or excessive fat accumulation that…

By 6 Min Read

Predicting Chronic Pain After Injury: 3-Day Window

The Connection Between Brain Connectivity, Anxiety, and Chronic Pain After Whiplash Injury After only one…

By 7 Min Read

Link between Ancient viral DNA and MS and ALS

Neurodegenerative diseases have long been a mystery to researchers, with their exact causes and mechanisms…

By 5 Min Read

Big data study shows RSV vaccine protects older adults

Respiratory syncytial virus, commonly known as RSV, is a serious respiratory infection that can have…

By 3 Min Read

Scientists identify crucial enzyme for healthy aging

A groundbreaking discovery has been made by a team at Kumamoto University in the field…

By 2 Min Read
MindBody Wellness Toolbox

At MindBodyWellnessToolbox.com, we provide reliable health and wellness information, practical tips, and product reviews to help you achieve a balanced and healthy lifestyle.

Quicklinks

  • Home
  • Nutrition and Diet
  • Fitness and Exercise
  • Mental Health
  • Weight Management
  • Chronic Conditions
  • Store

About US

  • Contact
  • About Us
  • Privacy Policy
  • Terms & Conditions
Copyright © 2024 MindBody Wellness Toolbox. All Rights Reserved.
Get Insider Tips

Gaining a competitive edge through the latest trends, innovative strategies, and insider information!

Zero spam, Unsubscribe at any time.